Ajmal Khan Selected Research

Glucosidases

4/2024	Synthesis of the chromone-thiosemicarbazone scaffold as promising α-glucosidase inhibitors: An in vitro and in silico approach toward antidiabetic drug design.
11/2023	Polyhydroquinoline derivatives for diabetic management: synthesis, in vitro and in silico approaches.
10/2023	Triazolothiadiazoles and triazolothiadiazines as potent α-glucosidase inhibitors: Mechanistic insights from kinetics studies, molecular docking and dynamics simulations.
3/2023	GC-MS Profiling and Biomedical Applications of Essential Oil of Euphorbia larica Boiss.: A New Report.
1/2023	Synthesis of new phenoxymethylcoumarin clubbed 4-arylthiazolylhydrazines as α-glucosidase inhibitors and their kinetics and molecular docking studies.
7/2022	Phenoxy pendant isatins as potent α-glucosidase inhibitors: reciprocal carbonyl⋯carbonyl interactions, antiparallel π⋯π stacking driven solid state self-assembly and biological evaluation.
11/2021	Synthesis of benzimidazole based hydrazones as non-sugar based α-glucosidase inhibitors: Structure activity relation and molecular docking.
5/2021	Rational Design of Novel Inhibitors of α-Glucosidase: An Application of Quantitative Structure Activity Relationship and Structure-Based Virtual Screening.
4/2021	Bio-Potency and Molecular Docking Studies of Isolated Compounds from Grewia optiva J.R. Drumm. ex Burret.
1/2021	Utilization of the common functional groups in bioactive molecules: Exploring dual inhibitory potential and computational analysis of keto esters against α-glucosidase and carbonic anhydrase-II enzymes.

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Ajmal Khan Research Topics

Disease

26	Neoplasms (Cancer) 03/2024 - 01/2013
13	Inflammation (Inflammations) 05/2024 - 06/2014
11	Infections 01/2024 - 10/2014
8	Pain (Aches) 05/2024 - 06/2014
8	Peptic Ulcer (Peptic Ulcers) 01/2024 - 01/2012
8	Edema (Dropsy) 11/2023 - 06/2014
7	Diabetes Mellitus 03/2024 - 01/2021
7	Alzheimer Disease (Alzheimer's Disease) 02/2023 - 01/2017
6	Hyperglycemia 01/2024 - 10/2014
6	Breast Neoplasms (Breast Cancer) 04/2023 - 10/2021
5	Neuralgia (Stump Neuralgia) 05/2024 - 01/2021
5	Type 2 Diabetes Mellitus (MODY) 04/2024 - 07/2019
5	Fever (Fevers) 01/2021 - 05/2012
5	Asthma (Bronchial Asthma) 01/2021 - 01/2011
4	Hyperalgesia 05/2024 - 01/2021
4	Body Weight (Weight, Body) 03/2024 - 07/2020
4	Lung Neoplasms (Lung Cancer) 11/2023 - 12/2007
4	COVID-19 04/2023 - 07/2021
4	Allergic Bronchopulmonary Aspergillosis 04/2020 - 01/2011
4	Hemorrhage 03/2020 - 07/2010
3	Cerebral Palsy (Spastic Diplegia) 03/2024 - 08/2018
3	Ulcer 01/2024 - 01/2012
3	Urolithiasis 01/2024 - 10/2014
3	Hepatic Encephalopathy 01/2024 - 10/2014
3	Gastritis 12/2023 - 01/2021
3	Pneumonia (Pneumonitis) 10/2023 - 07/2014
3	Virus Diseases (Viral Diseases) 12/2022 - 01/2017
2	Chronic Hepatitis C 01/2024 - 04/2023
2	Kidney Calculi (Kidney Stone) 12/2023 - 07/2021
2	Pulmonary Aspergillosis 11/2023 - 11/2022
2	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 06/2023 - 01/2023
2	Colorectal Neoplasms (Colorectal Cancer) 06/2023 - 01/2023
2	Triple Negative Breast Neoplasms 03/2023 - 09/2022
2	Amnesia (Dissociative Amnesia) 02/2023 - 01/2023
2	Leukemia 02/2023 - 06/2022
2	Vomiting 11/2022 - 01/2017
2	Neuroinflammatory Diseases 11/2022 - 11/2021
2	Peripheral Nervous System Diseases (PNS Diseases) 06/2022 - 01/2021
2	Lymphoma (Lymphomas) 06/2022 - 01/2016
2	Brain Neoplasms (Brain Tumor) 06/2022 - 01/2020
2	Glaucoma 01/2022 - 01/2020
2	Pancreatic Neoplasms (Pancreatic Cancer) 01/2022 - 01/2020
2	Neoplasm Metastasis (Metastasis) 01/2022 - 01/2019

Drug/Important Bio-Agent (IBA)

15	EnzymesIBA 02/2024 - 01/2012
14	GlucosidasesIBA 04/2024 - 10/2014
11	Proteins (Proteins, Gene)FDA Link 01/2024 - 07/2011
10	UreaseIBA 01/2024 - 01/2012
8	CarrageenanIBA 11/2023 - 06/2014
7	VaccinesIBA 02/2023 - 07/2021
5	PhytochemicalsIBA 03/2024 - 08/2016
5	Carbonic Anhydrase IIIBA 03/2023 - 01/2020
5	Member 1 Subfamily B ATP Binding Cassette TransporterIBA 01/2021 - 01/2015
4	Biomarkers (Surrogate Marker)IBA 05/2024 - 03/2023
4	Analgesics (Analgesic Drugs)IBA 01/2024 - 06/2014
4	CarbohydratesIBA 11/2023 - 01/2016
4	AcetylcholinesteraseIBA 02/2023 - 01/2018
4	EpitopesIBA 02/2023 - 01/2022
4	SesquiterpenesIBA 01/2023 - 01/2016
4	Acetic Acid (Vinegar)FDA LinkGeneric 01/2019 - 06/2014
3	AntioxidantsIBA 05/2024 - 01/2017
3	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 05/2024 - 01/2021
3	Blood Glucose (Blood Sugar)IBA 03/2024 - 03/2022
3	GlucocorticoidsIBA 11/2023 - 04/2012
3	Peptides (Polypeptides)IBA 10/2023 - 10/2021
3	Free RadicalsIBA 03/2023 - 01/2020
3	NF-kappa B (NF-kB)IBA 02/2023 - 01/2021
3	AcidsIBA 12/2021 - 01/2020
3	Anti-Bacterial Agents (Antibiotics)IBA 07/2021 - 06/2016
3	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2021 - 12/2007
2	ChromonesIBA 04/2024 - 01/2018
2	ThiosemicarbazonesIBA 04/2024 - 01/2021
2	AlloxanIBA 03/2024 - 09/2023
2	Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric 02/2024 - 04/2022
2	Antiviral Agents (Antivirals)IBA 01/2024 - 04/2023
2	flavoneIBA 01/2024 - 01/2021
2	Formaldehyde (Formol)FDA Link 01/2024 - 01/2019
2	Pentylenetetrazole (Metrazol)IBA 01/2024 - 01/2021
2	Ibuprofen (Motrin)FDA LinkGeneric 12/2023 - 04/2023
2	imidazoleIBA 11/2023 - 10/2022
2	Peptide Hydrolases (Proteases)FDA Link 08/2023 - 10/2018
2	CyclinsIBA 04/2023 - 01/2022
2	Hypoglycemic Agents (Hypoglycemics)IBA 03/2023 - 02/2023
2	AutoantibodiesIBA 03/2023 - 11/2022
2	Scopolamine (Hyoscine)FDA Link 02/2023 - 01/2023
2	ButyrylcholinesteraseIBA 02/2023 - 01/2018
2	RNA (Ribonucleic Acid)IBA 02/2023 - 01/2017
2	Cholinesterases (Cholinesterase)IBA 01/2023 - 11/2021
2	AntibodiesIBA 11/2022 - 07/2011
2	CytokinesIBA 11/2022 - 01/2020
2	Paclitaxel (Taxol)FDA LinkGeneric 06/2022 - 01/2021
2	Bicarbonates (Hydrogen Carbonate)IBA 01/2022 - 01/2020
2	FlavonoidsIBA 01/2022 - 04/2016
2	Terpenes (Terpenoids)IBA 01/2022 - 07/2017
2	OsteopontinIBA 01/2022 - 01/2019
2	SteroidsIBA 01/2022 - 01/2021
2	Matrix Metalloproteinases (MMPs)IBA 01/2022 - 01/2019
2	SaponinsIBA 01/2022 - 04/2014

Therapy/Procedure

22	Therapeutics 05/2024 - 01/2011
4	Drug Therapy (Chemotherapy) 03/2024 - 01/2016
2	Immunotherapy 03/2024 - 11/2022